PFIZER AND BIONTECH PROVIDE UPDATE ON OMICRON VARIANT
https://www.pfizer.com/news/press-release/press-release-detail/pfizer-and-biontech-provide-update-omicron-variant
Wednesday, December 08, 2021 - 06:54am
• Preliminary laboratory studies demonstrate that** three doses of the
Pfizer-BioNTech COVID-19 Vaccine neutralize the Omicron variant (B.1.1.529
lineage) while two doses show significantly reduced neutralization titers**
• Data indicate that a third dose of BNT162b2 increases the neutralizing
antibody titers by 25-fold compared to two doses against the Omicron variant;
titers after the booster dose are comparable to titers observed after two doses
against the wild-type virus which are associated with high levels of
protection
• As 80% of epitopes in the spike protein recognized by CD8+ T cells are not
affected by the mutations in the Omicron variant, two doses may still induce
protection against severe disease
• The companies continue to advance the development of a variant-specific
vaccine for Omicron and expect to have it available by March in the event that
an adaption is needed to further increase the level and duration of protection
– with no change expected to the companies’ four billion dose capacity for
2022
Omicron variant has "robust ability" to evade COVID vaccines, but
Pfizer says booster shots "neutralized" it
https://www.cbsnews.com/news/omicron-variant-covid-19-vaccines-news-pfizer-efficacy/
Johannesburg — South African scientists have released early data showing the
Omicron variant of the coronavirus has a "robust ability" to evade the immunity
offered by inoculation. But, as CBS News foreign correspondent Debora Patta
reports, it's not all bad news.
Pfizer and BioNTech said on Wednesday that while the standard two-dose regimen of their vaccine was "significantly less effective at blocking the virus," a booster shot "neutralized the Omicron variant in lab tests."